Krohg-Sørensen Kirsten, Rostad Hans, Geiran Odd R, Hafsahl Geir, Fosse Erik
Thoraxkirurgisk avdeling, Rikshospitalet 0027 Oslo.
Tidsskr Nor Laegeforen. 2002 Jan 30;122(3):274-7.
Endovascular stent-graft repair of abdominal aortic aneurysms was introduced in 1991. Long-term results from randomised studies are still not available. Aneurysm ruptures after stent-graft repair have been reported, and there has been a considerable need for redo procedures.
At Rikshospitalet in Oslo, Norway, 26 stent-graft implantations for abdominal aortic aneurysms were performed during the years 1996-2000, two of which were primary technical failures immediately converted to open repair. During follow-up, two patients have died from unrelated causes after six and 12 months. Eight patients were converted to open repair 8-50 months (median 31) after implantation. Indications for conversion were migration (n = 4), increasing aneurysm diameter (n = 3) and rupture (n = 1). Of the 14 patients still under observation, six have had one or more endovascular interventions (a total of 10) for failing graft.
Continuous technology development has been used as an argument to postpone randomised studies, as improved results are expected with new generations of stent-grafts. There is a need for discussion of the strategy for the further use of endovascular repair of abdominal aortic aneurysm.
腹主动脉瘤的血管内支架移植物修复术于1991年引入。随机研究的长期结果仍然不可得。已有支架移植物修复术后动脉瘤破裂的报道,并且对再次手术的需求相当大。
在挪威奥斯陆的Rikshospitalet,1996年至2000年期间对26例腹主动脉瘤进行了支架移植物植入,其中2例为原发性技术失败,立即转为开放修复。在随访期间,2例患者在6个月和12个月后死于无关原因。8例患者在植入后8至50个月(中位数31个月)转为开放修复。转为开放修复的指征为移位(n = 4)、动脉瘤直径增大(n = 3)和破裂(n = 1)。在仍在观察的14例患者中,6例因移植物功能衰竭接受了一次或多次血管内干预(共10次)。
持续的技术发展一直被用作推迟随机研究的理由,因为预计新一代支架移植物会有更好的结果。有必要讨论腹主动脉瘤血管内修复的进一步应用策略。