Michel F, Dujon B
Centre de Génétique Moléculaire, Laboratoire Propre du Centre National de la Recherche Scientifique, associé à l'Université Pierre et Marie Curie, Gif-sur-Yvette, France.
EMBO J. 1983;2(1):33-8. doi: 10.1002/j.1460-2075.1983.tb01376.x.
Two families of fungal mitochondrial introns that include all known sequences have been recognized. These families are now extended to incorporate a plant mitochondrial intron and several introns in chloroplast- and nuclear-encoded rRNA and tRNA precursors. Members of the same family share distinctive sequence stretches and a number of potential RNA secondary structures that would bring these stretches and the intron-exon junctions into relatively close proximity. Using several of these introns which have been extensively studied by either biochemical or genetic means, an attempt is made to integrate the available data into a common picture.
已识别出包含所有已知序列的两个真菌线粒体内含子家族。现在这些家族已扩展到纳入一个植物线粒体内含子以及叶绿体和核编码的rRNA和tRNA前体中的几个内含子。同一家族的成员共享独特的序列片段和一些潜在的RNA二级结构,这些结构会使这些片段和内含子 - 外显子连接相对靠近。利用其中几个已通过生化或遗传手段进行广泛研究的内含子,试图将现有数据整合到一个统一的图景中。