Einbrodt H J, Rosmanith J, Dreyhaupt F J, Schröder A
Zentralbl Bakteriol Orig B. 1975 Sep;161(1):38-45.
In a study of blood lead levels in 1719 children from 2 industrial areas, both with high but differing lead pollution, it is shown how the selection of the collective can influence the results of an epidemiological study. A representative statement on the lead exposure for all children living in a circumscribed area, is not possible if the children are selected according to previous diseases or, for that matter, according to medical criteria of any kind. Also, a selection only upon voluntary basis stemming from parental decision, does not bring correct results. The time chosen for the investigation must also be taken under consideration. The authors suggest a random choice, for example according to date of birth.
在一项针对来自两个工业区的1719名儿童血铅水平的研究中,这两个工业区铅污染程度都很高但有所不同,研究表明群体的选择方式会如何影响流行病学研究的结果。如果根据既往疾病或任何种类的医学标准来选择儿童,就不可能对生活在特定区域内的所有儿童的铅暴露情况做出具有代表性的陈述。同样,仅基于父母决定的自愿选择方式也不会得出正确结果。调查所选择的时间也必须予以考虑。作者建议采用随机选择方式,例如根据出生日期进行选择。