Zeschke G, Krasilnikow V G
Acta Biol Med Ger. 1975;34(4):593-602.
It is demonstrated by model experiments that the determination of stationary and instationary data (amplitude and shape of the heating signal) allows the two components of local brain perfusion (flow rate and volume flux) to be measured separately. Since perfusion and temperature are measured at the same site, the convection data are free of variations of the local brain temperature. The dependence of the amplitude of the heating signal on the flow rate is described by the equation Ao = a - e-bv + c, with the parameters a, b, c being represented as a function of the convection-free space around the sensing probe. It is shown by animal-experimental data that the magnitude of the convection-free space around the sensing probe is variable. A tentative algorithm is proposed for practical application of the method.
模型实验表明，通过测定稳态和非稳态数据（加热信号的幅度和形状），可以分别测量局部脑灌注的两个组成部分（流速和体积通量）。由于灌注和温度是在同一部位测量的，因此对流数据不受局部脑温变化的影响。加热信号幅度与流速的关系由方程Ao = a - e-bv + c描述，其中参数a、b、c表示为传感探头周围无对流空间的函数。动物实验数据表明，传感探头周围无对流空间的大小是可变的。针对该方法的实际应用提出了一种试探性算法。
