Ishihara M, Arai T, Sato S, Morimoto Y, Obara M, Kikuchi M
Department of Medical Engineering, National Defense Medical College, Tokorozawa, Saitama, Japan.
Front Med Biol Eng. 2001;11(3):167-75. doi: 10.1163/15685570152772441.
Measurement of the temperature of the corneal surface during photorefractive keratectomy (PRK) is thought to be useful for monitoring the corneal ablation process, since the photothermal process has been proposed as the major mechanism of ArF excimer laser ablation. For temperature measurement, we measured thermal radiation from the corneal surface during ArF excimer laser ablation using a mercury-cadmium-telluride detector with a 1-micros time constant. To investigate the effects of temperature on ablation depth, the ablation depth of the cornea was measured by microscopy. When corneal ablation was initiated at the fluence of 65 mJ/cm2, the corneal surface temperature rose to 60-70 degrees C. The energy required for a unit-depth ablation (degrees C/microm) was lowest at 120 micro C. Monitoring of transient temperature during PRK provides important information on energy-efficient ablation, which may enable rapid and safe corneal incisions.
在准分子激光原位角膜磨镶术（PRK）过程中测量角膜表面温度被认为有助于监测角膜消融过程，因为光热过程已被提出是ArF准分子激光消融的主要机制。为了进行温度测量，我们使用具有1微秒时间常数的碲镉汞探测器，在ArF准分子激光消融过程中测量角膜表面的热辐射。为了研究温度对消融深度的影响，通过显微镜测量角膜的消融深度。当以65 mJ/cm2的能量密度开始角膜消融时，角膜表面温度升至60 - 70摄氏度。单位深度消融所需的能量（摄氏度/微米）在120微摄氏度时最低。在PRK过程中监测瞬态温度可提供有关节能消融的重要信息，这可能实现快速且安全的角膜切割。
