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非传统微生物生物活性代谢产物。

Nontraditional microbial bioactive metabolites.

作者信息

Bĕhal V

机构信息

Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czechia.

出版信息

Folia Microbiol (Praha). 2001;46(5):363-70. doi: 10.1007/BF02814422.

Abstract

Microorganisms produce low-molar-mass secondary metabolites exhibiting different biological activities, which are used. e.g., in medicine as antimicrobial and antifungal agents, alkaloids and toxins. Some of these substances have highly diverse biological activities and unusual structures. They are produced by streptomycetes, fungi, and bacilli, but interesting products have also been obtained from microorganisms growing in extreme conditions. Several thousands of microbial products have so far been discovered and many other, which can be potentially useful and/or prospective for human use, can still be in the offing.

摘要

微生物产生具有不同生物活性的低摩尔质量次级代谢产物,这些产物被用于例如医学领域,作为抗菌和抗真菌剂、生物碱和毒素。其中一些物质具有高度多样的生物活性和独特的结构。它们由链霉菌、真菌和杆菌产生,但也从生长在极端条件下的微生物中获得了有趣的产物。到目前为止,已经发现了数千种微生物产物,许多其他可能对人类有用和/或有前景的产物仍可能即将出现。

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