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海洋真菌. 产生的次生代谢产物及其生物活性

Secondary Metabolites and Their Bioactivities Produced by .

机构信息

State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming 650091, China.

Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming 650091, China.

出版信息

Molecules. 2020 Nov 1;25(21):5077. doi: 10.3390/molecules25215077.

Abstract

, a common saprobic filamentous fungus, not only plays an important role in biological control, but also has applications in medicine, food, and environmental protection. In this paper, 223 secondary metabolites and their bioactivities from 13 known species and various unidentified strains of are reviewed. Their structures can be described as polyketide, terpenoid, peptide, alkaloid, quinone, pyrone, sterol, and fatty acid. They have been demonstrated varying biological activities, including antimicrobial, antitumor, insecticidal, antiplasmodial, antimalarial, nematicidal, herbicidal, and enzyme-inhibiting. This review provides a comprehensive overview of secondary metabolites and their biological activities from strains of .

摘要

球毛壳菌是一种常见的腐生丝状真菌,不仅在生物防治中发挥着重要作用,而且在医学、食品和环境保护领域也有应用。本文综述了 13 种已知种和各种未鉴定菌株的球毛壳菌产生的 223 种次生代谢产物及其生物活性。它们的结构可以描述为聚酮、萜类、肽、生物碱、醌、吡喃酮、甾体和脂肪酸。已证明它们具有不同的生物活性,包括抗菌、抗肿瘤、杀虫、抗疟原虫、抗疟、杀线虫、除草和抑制酶活性。本综述提供了球毛壳菌菌株次生代谢产物及其生物活性的全面概述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76ab/7663581/6111c4f8bd20/molecules-25-05077-g001.jpg

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