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Some nutritional factors influencing mevinolin production by Aspergillus terreus strain.

作者信息

Shindia A A

机构信息

Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, Egypt.

出版信息

Folia Microbiol (Praha). 2001;46(5):413-6. doi: 10.1007/BF02814431.

DOI:10.1007/BF02814431
PMID:11899474
Abstract

Aspergillus terreus produces the hypocholesterolemic compound mevinolin. Its growth and mevinolin production were affected by the composition of the culture medium. Both were at a maximum with glucose (6%) as the sole carbon source and in the presence of a mixture of yeast extract and sodium nitrate as nitrogen source. Influence of the concentration of some inorganic salts are also discussed.

摘要

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本文引用的文献

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Effects of Nitrogen Sources on Cellulose and Synthetic Lignin Degradation by Phanerochaete chrysosporium.氮源对黄孢原毛平革菌降解纤维素和合成木质素的影响。
Appl Environ Microbiol. 1983 Mar;45(3):838-42. doi: 10.1128/aem.45.3.838-842.1983.
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Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin.平菇子实体含有3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂——洛伐他汀。
Exp Mycol. 1995 Mar;19(1):1-6. doi: 10.1006/emyc.1995.1001.
6
Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.美伐他汀：一种高效的羟甲基戊二酰辅酶A还原酶竞争性抑制剂及降胆固醇药物。
Proc Natl Acad Sci U S A. 1980 Jul;77(7):3957-61. doi: 10.1073/pnas.77.7.3957.
7
Mevinolinic acid biosynthesis by Aspergillus terreus and its relationship to fatty acid biosynthesis.土曲霉合成美伐他汀酸及其与脂肪酸合成的关系。
J Bacteriol. 1985 May;162(2):704-7. doi: 10.1128/jb.162.2.704-707.1985.
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Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus ruber.
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Microbios. 1989;57(230):33-40.