Letwin R
Precision Therapeutics, Inc. Pittsburgh, PA,
Clin J Oncol Nurs. 2001 Sep-Oct;5(5):195-200.
Determining which chemotherapy treatment to administer to a patient with cancer is challenging because each patient's cancer is unique. Hundreds of different forms of cancer exist, and tumors of the same type or classification can have very different responses to the same, often standard, treatment. A scientifically-based analysis of how the chemotherapy options for an individual patient may affect that patient's specific tumor could benefit both the clinician and the patient. Chemosensitivity testing can provide this information. A Chemosensitivity assay is a laboratory test that is performed by isolating the cancer cells from a tumor specimen, exposing the cells to the desired chemotherapy agents, and evaluating the effectiveness of those agents. The results provide patient-specific tumor information.
确定对癌症患者采用哪种化疗方案具有挑战性,因为每个患者的癌症都是独特的。存在数百种不同形式的癌症,而且相同类型或分类的肿瘤对相同的(通常是标准的)治疗可能有非常不同的反应。对个体患者的化疗选择如何影响该患者的特定肿瘤进行基于科学的分析,可能会使临床医生和患者都受益。化疗敏感性测试可以提供此类信息。化疗敏感性测定是一种实验室检测,通过从肿瘤标本中分离癌细胞,将细胞暴露于所需的化疗药物,并评估这些药物的有效性来进行。结果提供了针对患者的肿瘤信息。