Kam L A, Giacoia G P
Am J Dis Child. 1975 Oct;129(10):1215-8. doi: 10.1001/archpedi.1975.02120470059017.
Two cases of congenital cutaneous candidiasis are presented in order to call attention to this rarely recognized and infrequently reported condition. Clinical features and appropriate cultures are useful in differentiating the lesions from other more common dermatoses of the neonatal period. Microscopic examination of the placenta may disclose fungal funisitis or chorioamnionitis, thus defining the congenital nature of the disease. Topical antifungal therapy is sufficient unless systemic candidiasis is present. No evidence of impaired immunological responsiveness was found in the two infants.
本文报告两例先天性皮肤念珠菌病，以引起对这种罕见且报道较少的疾病的关注。临床特征和适当的培养有助于将这些皮损与新生儿期其他更常见的皮肤病相鉴别。胎盘的显微镜检查可能会发现真菌性脐带炎或绒毛膜羊膜炎，从而确定该疾病的先天性本质。除非存在全身性念珠菌病，局部抗真菌治疗就足够了。在这两名婴儿中未发现免疫反应受损的证据。
