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本文引用的文献

1
Inability of Short-duration Treatment with a 5-Lipoxy-genase Inhibitor to Reduce Clinical Signs of Canine Atopy.5-脂氧合酶抑制剂短期治疗无法减轻犬特应性皮炎的临床症状。
Vet Dermatol. 1994 Mar;5(1):13-16. doi: 10.1111/j.1365-3164.1994.tb00004.x.
2
Double-blinded, placebo-controlled, cross-over pilot study on the efficacy of zileuton for canine atopic dermatitis.
Vet Dermatol. 2001 Aug;12(4):189-95. doi: 10.1046/j.0959-4493.2001.00254.x.
3
Sulphido-leukotriene production from peripheral leukocytes and skin in clinically normal dogs and house dust mite positive atopic dogs.临床正常犬和屋尘螨阳性特应性犬外周白细胞及皮肤中硫化白三烯的产生情况
Vet Dermatol. 2001 Feb;12(1):3-12. doi: 10.1046/j.1365-3164.2001.00203.x.
4
The leukotriene antagonist montelukast as a therapeutic agent for atopic dermatitis.白三烯拮抗剂孟鲁司特作为特应性皮炎的治疗药物。
J Am Acad Dermatol. 2001 Jan;44(1):89-93. doi: 10.1067/mjd.2001.111352.
5
Treatment of atopic dermatitis with zafirlukast.
Dermatol Online J. 1999 Nov;5(2):10.
6
A pilot study examining the role of zileuton in atopic dermatitis.一项探讨齐留通在特应性皮炎中作用的初步研究。
Ann Allergy Asthma Immunol. 1999 Dec;83(6 Pt 1):548-52. doi: 10.1016/S1081-1206(10)62868-2.
7
Antihistamines in the management of allergic pruritus in dogs and cats.
J Small Anim Pract. 1999 Aug;40(8):359-64. doi: 10.1111/j.1748-5827.1999.tb03099.x.
8
Chemical mediators in atopic dermatitis: involvement of leukotriene B4 released by a type I allergic reaction in the pathogenesis of atopic dermatitis.特应性皮炎中的化学介质：I型过敏反应释放的白三烯B4在特应性皮炎发病机制中的作用。
J Allergy Clin Immunol. 1999 Apr;103(4):663-70. doi: 10.1016/s0091-6749(99)70240-x.
9
Metabolism and excretion of zafirlukast in dogs, rats, and mice.扎鲁司特在犬、大鼠和小鼠体内的代谢与排泄。
Drug Metab Dispos. 1998 Nov;26(11):1069-76.
10
The leukotriene antagonist zafirlukast as a therapeutic agent for atopic dermatitis.
Arch Dermatol. 1998 Jul;134(7):785-6. doi: 10.1001/archderm.134.7.785.

用白三烯受体拮抗剂扎鲁司特治疗犬异位性皮炎：一项单盲、安慰剂对照研究。

Treatment of canine atopic dermatitis with zafirlukast, a leukotriene-receptor antagonist: a single-blinded, placebo-controlled study.

作者信息

Senter David A, Scott Danny W, Miller William H

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853-6401, USA.

出版信息

Can Vet J. 2002 Mar;43(3):203-6.

PMID:11901593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC339203/
Abstract

Zafirlukast and placebo were administered orally as individual agents to 20 dogs with atopic dermatitis. The pruritus was effectively reduced by at least 50% in 2/18 (11%) dogs that completed the trial with zafirlukast. Two dogs vomited after administration of the active drug.

摘要

将扎鲁司特和安慰剂分别口服给予20只患有特应性皮炎的犬。在完成扎鲁司特试验的18只犬中，有2只（11%）的瘙痒症状有效减轻了至少50%。两只犬在服用活性药物后呕吐。