Silber Michael H, Krahn Lois E, Olson Eric J, Pankratz V Shane
Sleep Disorders Center, Department of Neurology, Mayo Clinic and Mayo Medical School, Rochester, Minnesota 55905, USA.
Sleep. 2002 Mar 15;25(2):197-202. doi: 10.1093/sleep/25.2.197.
To determine the age- and sex-specific incidence rates and prevalence of narcolepsy in a United States community.
The records-linkage system of the Rochester Epidemiology Project was utilized to ascertain all patients with narcolepsy seen in Olmsted County, Minnesota between 1960 and 1989. Age- and sex-specific incidence rates were calculated, using census data. Prevalence of narcolepsy on January 1,1985 was calculated.
N/A.
Community patients diagnosed with narcolepsy by a validated set of diagnostic criteria.
N/A.
The incidence rate per 100,000 persons per year was 1.37 (1.72 for men and 1.05 for women). The incidence rate was highest in the 2nd decade, followed in descending order by the 3rd, 4th and 1st decades. The prevalence on January 1, 1985 was 56.3 per 100,000 persons. Approximately 36% of prevalence cases did not have cataplexy.
Narcolepsy is not a rare disorder. It appears to be commoner in men. It originates most commonly in the 2nd decade. Narcolepsy without cataplexy is an important subgroup, warranting further study.
确定美国一个社区发作性睡病的年龄和性别特异性发病率及患病率。
利用罗切斯特流行病学项目的记录链接系统，确定1960年至1989年间明尼苏达州奥尔姆斯特德县所有发作性睡病患者。使用人口普查数据计算年龄和性别特异性发病率。计算1985年1月1日发作性睡病的患病率。
无。
根据一套经过验证的诊断标准被诊断为发作性睡病的社区患者。
无。
每年每10万人的发病率为1.37（男性为1.72，女性为1.05）。发病率在第二个十年最高，其次依次为第三个、第四个和第一个十年。1985年1月1日的患病率为每10万人56.3。约36%的患病病例没有猝倒症。
发作性睡病并非罕见疾病。在男性中似乎更为常见。最常见于第二个十年发病。无猝倒症的发作性睡病是一个重要的亚组，值得进一步研究。
