Prince H Miles, O'Keefe Rod, McCormack Christopher, Ryan Gail, Turner Hugh, Waring Paul, Baker Chris
Division of Haematology and Medical Oncology, Peter MacCallum Cancer Institute, Melbourne, Victoria, Australia.
Pathology. 2002 Feb;34(1):36-45. doi: 10.1080/00313020120105615.
Cutaneous lymphomas are rare and although some are a manifestation of systemic lymphoma, the majority arise primarily from the skin. These primary cutaneous lymphomas comprise predominantly T cell subtypes and represent a wide spectrum of disorders. Pathologists can currently choose to label these conditions according to three classifications (REAL, EORTC or WHO) but each has shortcomings. Nonetheless, in an attempt to unify the field, we would recommend that pathologists make every attempt to categorise these conditions according to the WHO classification. This classification can encompass all the conditions and aligns the cutaneous lymphomas with the broader systemic lymphoproliferative conditions.
皮肤淋巴瘤较为罕见,虽然有些是全身性淋巴瘤的一种表现,但大多数主要起源于皮肤。这些原发性皮肤淋巴瘤主要包括T细胞亚型,代表了广泛的疾病谱。目前病理学家可以选择根据三种分类(REAL、EORTC或WHO)来标记这些疾病,但每种分类都有缺点。尽管如此,为了统一该领域,我们建议病理学家尽可能根据WHO分类对这些疾病进行分类。这种分类可以涵盖所有疾病,并使皮肤淋巴瘤与更广泛的全身性淋巴增殖性疾病保持一致。