Schneyer L H
Am J Physiol. 1975 Oct;229(4):1056-61. doi: 10.1152/ajplegacy.1975.229.4.1056.
Stimulation of the sympathetic innervation to rat submaxillary gland is known to evoke saliva which contains high concentrations of potassium (130-160 meq/liter). Relationships were examined between salivary [K] and several parameters of the stimulation, including pulse frequency and duration of the stimulus train and rate of flow of the evoked saliva. Secretion of sympathetically evoked saliva was found to occur in two phases. After stimulation was started, flow rate was relatively high initially, and then decreased to a lower, relatively steady value. Initial and steady flow rates were maximal when stimulus frequency was 10 Hz. Salivary [K] was lowest initially, and, at that time, was inversely related to flow rate. At steady flow, [K] was flow independent. While salivary [K] was lower during initial than during steady secretion, the rate of K secretion was initially higher. During the initial phase, K decreased in the gland, and this decrease was sufficient to account for the increased amount of K secreted in initial saliva and for the increased initial flow.
已知刺激大鼠颌下腺的交感神经支配会引起唾液分泌，所分泌的唾液含有高浓度的钾（130 - 160毫当量/升）。研究了唾液中钾含量与刺激的几个参数之间的关系，包括脉冲频率、刺激序列的持续时间以及诱发唾液的流速。发现交感神经诱发的唾液分泌分两个阶段进行。刺激开始后，最初流速相对较高，然后降至较低的相对稳定值。当刺激频率为10赫兹时，初始流速和稳定流速最大。唾液中钾含量最初最低，且此时与流速呈负相关。在稳定流速时，钾含量与流速无关。虽然初始分泌时唾液中钾含量低于稳定分泌时，但钾的分泌速率最初较高。在初始阶段，腺体中的钾含量下降，这种下降足以解释初始唾液中分泌的钾量增加以及初始流速增加的原因。
