Tay C H, Yap E H, Singh M L, Simons M J
Ann Allergy. 1975 Nov;35(5):312-22.
Serum IgE was determined in four groups of Singapore Chinese consisting of 292 normal subjects, 15 patients with atopic dermatitis, 39 with drug allergy and 14 with bronchial asthma. The results were compared with the findings of similar groups in western countries. In the normal subjects the range and means (numerical and geometrical) of serum IgE were four to seven times higher in the Singapore Chinese than reported in the western countries. However, the circulating levels in atopic dermatitis and bronchial asthma patients were comparable. In drug allergy moderate IgE elevation was noted. The serum IgE levels of the normal subjects and patients with atopic dermatitis and bronchial asthma were markedly lower than those found in nearby Papua New Guinea. The significance of these observations is discussed.
对四组新加坡华人进行了血清免疫球蛋白E（IgE）检测，这四组包括292名正常受试者、15名特应性皮炎患者、39名药物过敏患者和14名支气管哮喘患者。将结果与西方国家类似组的研究结果进行了比较。在正常受试者中，新加坡华人血清IgE的范围和均值（数值和几何均值）比西方国家报道的高4至7倍。然而，特应性皮炎和支气管哮喘患者的循环水平相当。在药物过敏患者中，观察到IgE适度升高。正常受试者、特应性皮炎患者和支气管哮喘患者的血清IgE水平明显低于附近巴布亚新几内亚的人群。讨论了这些观察结果的意义。
