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化学性和热性眼烧伤的急诊治疗

Emergency treatment of chemical and thermal eye burns.

作者信息

Kuckelkorn Ralf, Schrage Norbert, Keller Gabriela, Redbrake Claudia

机构信息

Department of Ophthalmology, Universitätsklinikum der RWTH Aachen, Germany.

出版信息

Acta Ophthalmol Scand. 2002 Feb;80(1):4-10. doi: 10.1034/j.1600-0420.2002.800102.x.

Abstract

Chemical and thermal eye burns account for a small but significant fraction of ocular trauma. The speed at which initial irrigation of the eye begins, has the greatest influence on the prognosis and outcome of eye burns. Water is commonly recommended as an irrigation fluid. However, water is hypotonic to the corneal stroma. The osmolarity gradient causes an increased water influx into the cornea and the invasion of the corrosive substance into deeper corneal structures. We therefore recommend higher osmolarities for the initial rinsing to mobilize water and the dissolved corrosives out of the burnt tissue. Universal systems such as amphoteric solutions, which have an unspecific binding with bases and acids, provide a convenient solution for emergency neutralisation. Both conservative anti-inflammatory therapy and early surgical intervention are important to reduce the inflammatory response of the burnt tissue. In most severe eye burns, tenonplasty re-establishes the conjunctival surface and limbal vascularity and prevents anterior segment necrosis.

摘要

化学性和热性眼烧伤在眼外伤中占比虽小但意义重大。眼部初始冲洗开始的速度对眼烧伤的预后和结局影响最大。通常推荐用水作为冲洗液。然而,水相对于角膜基质是低渗的。渗透压梯度会导致更多水分流入角膜,使腐蚀性物质侵入更深层的角膜结构。因此,我们建议初始冲洗采用较高渗透压,以便将水分和溶解的腐蚀性物质从烧伤组织中排出。通用系统如两性溶液,可与碱和酸进行非特异性结合,为紧急中和提供了便捷的解决方案。保守的抗炎治疗和早期手术干预对于减轻烧伤组织的炎症反应都很重要。在大多数严重眼烧伤中,睑球结膜移植术可重建结膜表面和角膜缘血管,并防止前段坏死。

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