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冰岛类风湿因子的人群研究。对50名患有类风湿因子(RF)的女性进行5年随访。

A population study of rheumatoid factor in Iceland. A 5-year follow-up of 50 women with rheumatoid factor (RF).

作者信息

Thorsteinsson J, Björnsson O J, Kolbeinsson A, Allander E, Sigfússon N, Olafsson O

出版信息

Ann Clin Res. 1975 Jun;7(3):183-94.

PMID:1190700
Abstract

The subject of this paper is a 5-year follow-up of 50 women found with Rose-Waaler Titre greater than or equal 1 : 10 or with a Acryl Fixation Titre greater than or equal 1 : 10 in a general health survey conducted in the Reykjavik area in 1968-1969. The average annual incidence of RA was 2.3 percent. Of four women who died during the follow-up period, three were amongst those with the highest titres. Two of the decreased had cancer mammae and one had lung cancer. Changes in RF-titres and New York Criteria are also discussed. It is suggested that RF-positives could be divided in three different riskgroups.

摘要

本文的研究对象是对1968 - 1969年在雷克雅未克地区进行的一项普通健康调查中发现的50名女性进行为期5年的随访,这些女性的罗斯 - 瓦勒滴度大于或等于1:10,或丙烯酸固定滴度大于或等于1:10。类风湿关节炎的年平均发病率为2.3%。在随访期间死亡的4名女性中,有3名滴度最高。其中2名患有乳腺癌,1名患有肺癌。还讨论了类风湿因子滴度的变化和纽约标准。建议将类风湿因子阳性者分为三个不同的风险组。

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