Kim B H, Sithian N, Cucolo G F
Arch Surg. 1975 Oct;110(10):1246-8. doi: 10.1001/archsurg.1975.01360160084015.
A subcutaneous mass removed from the cheek showed histologic features of subcutaneous angiolymphoid hyperplasia (Kimura disease) at its early stage. The condition shows a wide spectrum of pathologic changes. At its early stage, the main findings consist of active vascular proliferation with plump endothelial cells and varying degrees of lymphocytic, histiocytic, and eosinophilic infiltration. The lesion at its later stage features hyperplastic blood vessels with inconspicuous endothelial cells, well-formed lymphoid follicles, and varying degrees of lymphocytic and eosinophilic infilitration. Blood eosinophilia is frequently seen. Review of the literature and study of our own case strongly suggest that this disease is a distinct clinical and pathologic entity.
从脸颊切除的一个皮下肿物在早期显示出皮下血管淋巴样增生(木村病)的组织学特征。该病症呈现出广泛的病理变化。在早期,主要表现为血管内皮细胞饱满的活跃血管增生以及不同程度的淋巴细胞、组织细胞和嗜酸性粒细胞浸润。后期病变的特征为血管增生,内皮细胞不明显,有形成良好的淋巴滤泡,以及不同程度的淋巴细胞和嗜酸性粒细胞浸润。常可见血液嗜酸性粒细胞增多。文献复习及对我们自身病例的研究强烈提示,本病是一种独特的临床和病理实体。