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动脉酰基辅酶A:胆固醇酰基转移酶和胆固醇酯水解酶活性。

The arterial acyl-CoA:cholesterol acyltransferase and cholesterol ester hydrolase activities.

作者信息

Patelski J, Pniewska B, Pioruńska M

出版信息

Atherosclerosis. 1975 Sep-Oct;22(2):287-91. doi: 10.1016/0021-9150(75)90009-x.

DOI:10.1016/0021-9150(75)90009-x
PMID:1191377
Abstract

Cholesterol acyltransferase and cholesterol esterase activities of protein extracts from pig aortas have been examined and the rations of synthesis/hydrolysis rates in the presence of substrates with different fatty acids estimated. The values obtained were in the numerical order: cholesteryl oleate greater than palmitate greater than or equal to linoleate greater than linolenate greater than staerate. The results are discussed in relation to the known different accumulation of cholesterol esters in the arterial wall.

摘要

已对猪主动脉蛋白质提取物中的胆固醇酰基转移酶和胆固醇酯酶活性进行了检测,并估算了在存在不同脂肪酸底物的情况下合成/水解速率的比值。所得数值按以下顺序排列:油酸胆固醇酯大于棕榈酸胆固醇酯大于或等于亚油酸胆固醇酯大于亚麻酸胆固醇酯大于硬脂酸胆固醇酯。结合动脉壁中已知的胆固醇酯不同积累情况对结果进行了讨论。

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