底物组成和浓度对主动脉胆固醇酯水解酶活性的影响。
Effect of substrate composition and concentration on aortic cholesterol ester hydrolase activity.
作者信息
Patelski J, Pioruńska A, Pioruńska-Stolzmann M
出版信息
Enzyme. 1978;23(2):135-9. doi: 10.1159/000458564.
PMID:25174
Abstract
Cholesterol ester hydrolase activity of pig aorta has been examined under optimum experimental conditions for hydrolysis of different cholesterol esters. The enzyme specific activity values were in the numerical order of substrates hydrolyzed: cholesteryl linoleate larger than or equal to linolenate greater than palmitate larger than or equal to stearate greater than oleate. The results are discussed in relation to the arterial accumulation of cholesterol esters.
摘要
在不同胆固醇酯水解的最佳实验条件下，对猪主动脉的胆固醇酯水解酶活性进行了检测。酶的比活性值按底物水解的数值顺序排列：亚油酸胆固醇酯大于或等于亚麻酸胆固醇酯大于棕榈酸胆固醇酯大于或等于硬脂酸胆固醇酯大于油酸胆固醇酯。结合胆固醇酯在动脉中的蓄积情况对结果进行了讨论。
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