• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Candida endocarditis treated with a combination of antifungal chemotherapy and aortic valve replacement.采用抗真菌化疗与主动脉瓣置换术联合治疗念珠菌性心内膜炎。
Br Heart J. 1975 Nov;37(11):1191-4. doi: 10.1136/hrt.37.11.1191.
2
Torulopsis glabrata endocarditis complicating aortic homograft valve treated with 5-fluorocytosine: case report with discussion of antifungal chemotherapy.
N Z Med J. 1975 Mar 26;81(536):294-8.
3
Candida endocarditis in two patients.两名患者的念珠菌性心内膜炎。
Arch Intern Med. 1976 Feb;136(2):208-12.
4
[First medical cure of Candida endocarditis on a valve prosthesis].[首例人工瓣膜上念珠菌性心内膜炎的药物治愈]
Ann Med Interne (Paris). 1977 Aug-Sep;128(8-9):699-703.
5
Candida parapsilosis: an unusual organism causing prosthetic heart valve infective endocarditis.近平滑念珠菌：一种引起人工心脏瓣膜感染性心内膜炎的罕见病原体。
J Infect. 1999 Mar;38(2):130-1. doi: 10.1016/s0163-4453(99)90084-1.
6
[Candida endocarditis in mitral prosthesis (apropos of a case cured by a second operation)].[二尖瓣人工瓣膜念珠菌性心内膜炎（关于 1 例经二次手术治愈的病例）]
Arch Mal Coeur Vaiss. 1973 Sep;66(9):1211-6.
7
[A successfully treated case of infective endocarditis due to Candida tropicalis].
Kansenshogaku Zasshi. 1990 May;64(5):636-41. doi: 10.11150/kansenshogakuzasshi1970.64.636.
8
Candida endocarditis treated with 5-fluorocytosine.用5-氟胞嘧啶治疗的念珠菌性心内膜炎。
Br Med J. 1971 Jan 30;1(5743):262-4. doi: 10.1136/bmj.1.5743.262.
9
Candida endocarditis complicating glucose total intravenous nutrition.念珠菌性心内膜炎并发葡萄糖全胃肠外营养
Ann Surg. 1974 Jun;179(6):902-5. doi: 10.1097/00000658-197406000-00014.
10
Tissue penetration of amphotericin B in Candida endocarditis.两性霉素B在念珠菌性心内膜炎中的组织穿透情况。
Chest. 1974 Oct;66(4):376-7. doi: 10.1378/chest.66.4.376.

引用本文的文献

1
Fungal endocarditis: patients at risk and their treatment.真菌性心内膜炎：高危患者及其治疗
Postgrad Med J. 1979 Sep;55(647):632-41. doi: 10.1136/pgmj.55.647.632.

本文引用的文献

1
Surgical treatment of candida endocarditis.
JAMA. 1968 Feb 26;203(9):621-6.
2
Treatment of disseminated mycotic infectioons. A new approach to amphotericin B therapy.播散性霉菌感染的治疗。两性霉素B治疗的新方法。
Am J Med. 1968 Sep;45(3):405-18. doi: 10.1016/0002-9343(68)90075-2.
3
Candida endocarditis treated with 5-fluorocytosine.用5-氟胞嘧啶治疗的念珠菌性心内膜炎。
Br Med J. 1971 Jan 30;1(5743):262-4. doi: 10.1136/bmj.1.5743.262.
4
Synergistic action of amphotericin B and 5-fluorocytosine against yeast-like organisms.两性霉素B与5-氟胞嘧啶对酵母样菌的协同作用。
Proc Soc Exp Biol Med. 1971 Nov;138(2):571-4. doi: 10.3181/00379727-138-35943.
5
Fungal endocarditis secondary to drug addiction. Recent concepts in diagnosis and therapy.
J Thorac Cardiovasc Surg. 1972 Jun;63(6):980-5.
6
Patterns of Candida endocarditis following cardiac surgery: Importance of early diagnosis and therapy (an analysis of 91 cases).心脏手术后念珠菌性心内膜炎的模式：早期诊断和治疗的重要性（91例分析）
Prog Cardiovasc Dis. 1974 Sep-Oct;17(2):125-60. doi: 10.1016/0033-0620(74)90027-9.
7
Pharmacological studies with 5-fluorocytosine.5-氟胞嘧啶的药理学研究。
Antimicrob Agents Chemother. 1972 Jun;1(6):476-82. doi: 10.1128/AAC.1.6.476.
8
Candida endocarditis after cardiac surgery. Clues to earlier detection.心脏手术后的念珠菌性心内膜炎。早期检测线索。
J Thorac Cardiovasc Surg. 1973 Apr;65(4):583-601.
9
The combined effect of 5-fluorocytosine and amphotericin B in the therapy of murine cryptococcosis.5-氟胞嘧啶与两性霉素B联合治疗小鼠隐球菌病的效果
Proc Soc Exp Biol Med. 1973 Feb;142(2):476-80. doi: 10.3181/00379727-142-37049.
10
C. albicans resistance to 5-fluorocytosine.白色念珠菌对5-氟胞嘧啶的耐药性。
Br Med J. 1972 Aug 26;3(5825):531. doi: 10.1136/bmj.3.5825.531.

采用抗真菌化疗与主动脉瓣置换术联合治疗念珠菌性心内膜炎。

Candida endocarditis treated with a combination of antifungal chemotherapy and aortic valve replacement.

作者信息

Stone D L

出版信息

Br Heart J. 1975 Nov;37(11):1191-4. doi: 10.1136/hrt.37.11.1191.

DOI:10.1136/hrt.37.11.1191
PMID:1191435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC482938/
Abstract

A case of Candida albicans endocarditis is described in which treatment with 5-fluorocytosine was started after aortic valve replacement, but relapse followed discontinuance of treatment. At a second operation the aortic valve was replaced under 5-fluorocytosine cover and treatment was continued with both 5-fluorocytosine and amphotericin-B. No resistance to 5-fluorocytosine developed, and the candida infection was eradicated. The patient is well 22 months after his operation.

摘要

本文描述了一例白色念珠菌性心内膜炎病例，该患者在主动脉瓣置换术后开始使用5-氟胞嘧啶治疗，但治疗中断后复发。在第二次手术中，在5-氟胞嘧啶覆盖下更换了主动脉瓣，并继续使用5-氟胞嘧啶和两性霉素B进行治疗。未出现对5-氟胞嘧啶的耐药性，念珠菌感染得以根除。患者术后22个月情况良好。