用5-氟胞嘧啶治疗的念珠菌性心内膜炎。
Candida endocarditis treated with 5-fluorocytosine.
作者信息
Record C O, Skinner J M, Sleight P, Speller D C
出版信息
Br Med J. 1971 Jan 30;1(5743):262-4. doi: 10.1136/bmj.1.5743.262.
Abstract
Three patients with endocarditis due to Candida species were treated with 5-fluorocytosine. One had endocarditis imposed on senile aortic sclerosis and survived and two had infections on prosthetic valves and died. In the latter two patients chemotherapy failed to eradicate the infection and was associated with marrow depression and possibly hepatic necrosis.
摘要
三名念珠菌属引起的心内膜炎患者接受了5-氟胞嘧啶治疗。一名患者的心内膜炎并发于老年主动脉硬化，存活下来；另外两名患者的人工瓣膜发生感染，死亡。在后两名患者中，化疗未能根除感染，且伴有骨髓抑制，并可能导致肝坏死。
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