• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

急性肾衰竭时抗纤溶酶活性增强。

Enhanced antiplasmin activity in acute renal failure.

作者信息

Kanfer A, Vandewalle A, Beaufils M, Delarue F, Sraer J D

出版信息

Br Med J. 1975 Oct 25;4(5990):195-7. doi: 10.1136/bmj.4.5990.195.

DOI:10.1136/bmj.4.5990.195
PMID:1191995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1674993/
Abstract

Plasmatic slow plasmin-inhibitor activity was assessed in 20 patients with acute renal failure and 12 controls with the fibrin plate method. The area of fibrinolysis was 250-5 +/- 5 mm2 in the patients and 289 +/- 6mm2 in the controls (P less than 0.001) and was negatively correlated with antiplasmin activity. Thirteen patients had areas of lysis equal to or inferior to the minimal lysis observed in the controls. No correlation was found between antiplasmin activity and serum fibrin-fibrinogen related antigen titres, the presence or absence of disseminated intravascular coagulation, or the causative disease.

摘要

采用纤维蛋白平板法对20例急性肾衰竭患者和12例对照者的血浆慢纤溶酶抑制活性进行了评估。患者的纤溶面积为250 - 5±5mm²,对照者为289±6mm²(P<0.001),且与抗纤溶酶活性呈负相关。13例患者的溶解面积等于或低于对照者中观察到的最小溶解面积。未发现抗纤溶酶活性与血清纤维蛋白 - 纤维蛋白原相关抗原滴度、是否存在弥散性血管内凝血或致病疾病之间存在相关性。

相似文献

1
Enhanced antiplasmin activity in acute renal failure.急性肾衰竭时抗纤溶酶活性增强。
Br Med J. 1975 Oct 25;4(5990):195-7. doi: 10.1136/bmj.4.5990.195.
2
[Molecular markers of hemostatic-mechanisms--plasmin-alpha 2 plasmin inhibitor complex].[止血机制的分子标志物——纤溶酶-α2纤溶酶抑制剂复合物]
Rinsho Byori. 1989 Mar;37(3):248-55.
3
[Intravascular coagulation in acute promyelocytic leukemia: analysis of coagulation and fibrinolysis parameters].[急性早幼粒细胞白血病中的血管内凝血:凝血与纤维蛋白溶解参数分析]
Rev Med Chil. 1991 Sep;119(9):984-9.
4
[Coagulation and fibrinolysis parameters in disseminated intravascular coagulation (DIC)].[弥散性血管内凝血(DIC)中的凝血与纤维蛋白溶解参数]
Rinsho Byori. 1991 Mar;39(3):309-14.
5
Fibrinolysis and fibrinogenolysis in disseminated intravascular coagulation.弥散性血管内凝血中的纤维蛋白溶解和纤维蛋白原溶解
Thromb Haemost. 1990 Jun 28;63(3):340-4.
6
Activation of both coagulation and fibrinolysis in childhood hemolytic uremic syndrome.儿童溶血尿毒综合征中凝血和纤溶的激活。
Kidney Int. 1998 Oct;54(4):1324-30. doi: 10.1046/j.1523-1755.1998.00103.x.
7
Coagulofibrinolytic changes in patients with disseminated intravascular coagulation associated with post-cardiac arrest syndrome--fibrinolytic shutdown and insufficient activation of fibrinolysis lead to organ dysfunction.弥散性血管内凝血相关心搏骤停后综合征患者的凝血-纤溶变化——纤溶抑制和纤溶激活不足导致器官功能障碍。
Thromb Res. 2013 Jul;132(1):e64-9. doi: 10.1016/j.thromres.2013.05.010. Epub 2013 May 30.
8
Characterization of the fibrinolytic state by measuring stable cross-linked fibrin degradation products in disseminated intravascular coagulation associated with acute promyelocytic leukemia.通过测量与急性早幼粒细胞白血病相关的弥散性血管内凝血中稳定交联纤维蛋白降解产物来表征纤溶状态。
Acta Haematol. 1989;81(1):15-8. doi: 10.1159/000205392.
9
Acute renal failure.急性肾衰竭
Lancet. 1973 Aug 11;2(7824):328. doi: 10.1016/s0140-6736(73)90838-6.
10
[Changes in coagulation and fibrinolysis cascades upon extracorporeal circulation].体外循环时凝血和纤溶系统的变化
Nihon Rinsho. 1991 Dec;49 Suppl:81-6.

引用本文的文献

1
Acute Kidney Injury in Decompensated Cirrhosis Is Associated With Both Hypo-coagulable and Hyper-coagulable Features.失代偿期肝硬化中的急性肾损伤与低凝和高凝特征均有关。
Hepatology. 2020 Oct;72(4):1327-1340. doi: 10.1002/hep.31443.

本文引用的文献

1
Thrombotic disorders with increased levels of antiplasmin and antiplasminogen.
N Engl J Med. 1961 Nov 2;265:867-71. doi: 10.1056/NEJM196111022651801.
2
Studies of the plasmin system. II. Inhibition of plasmin by serum or plasma.纤溶酶系统的研究。II. 血清或血浆对纤溶酶的抑制作用。
J Exp Med. 1958 Jul 1;108(1):53-68. doi: 10.1084/jem.108.1.53.
3
The fibrin plate method for estimating fibrinolytic activity.用于评估纤维蛋白溶解活性的纤维蛋白平板法。
Arch Biochem Biophys. 1952 Oct;40(2):346-51. doi: 10.1016/0003-9861(52)90121-5.
4
Contributions to renal pathology through the use of the electron microscope: glomerular changes.通过使用电子显微镜对肾脏病理学的贡献:肾小球变化
Isr J Med Sci. 1967 Jan-Feb;3(1):191-7.
5
Fibrinolytic enzyme system and pregnancy.纤溶酶系统与妊娠
Br Med J. 1969 Aug 16;3(5667):387-9. doi: 10.1136/bmj.3.5667.387.
6
Glomerular capillary thrombosis and acute renal failure after epsilon-amino caproic acid therapy.ε-氨基己酸治疗后出现肾小球毛细血管血栓形成及急性肾衰竭。
N Engl J Med. 1969 May 15;280(20):1102-4. doi: 10.1056/NEJM196905152802006.
7
Glomerular coagulation in acute ischaemic renal failure.急性缺血性肾衰竭中的肾小球凝血
Q J Med. 1970 Oct;39(156):585-99.
8
Intravascular clotting and acute renal failure.血管内凝血与急性肾衰竭。
Scand J Haematol Suppl. 1971;13:337-43. doi: 10.1111/j.1600-0609.1971.tb02033.x.
9
The detection of fibrinogen-fibrin degradation products by means of a new antibody-coated latex particle.采用新型抗体包被乳胶颗粒检测纤维蛋白原 - 纤维蛋白降解产物。
J Clin Pathol. 1972 Aug;25(8):680-2. doi: 10.1136/jcp.25.8.680.
10
Clinical experience with determination of fibrinogen degradation products.纤维蛋白原降解产物测定的临床经验
Acta Med Scand. 1971 Jun;189(6):471-7. doi: 10.1111/j.0954-6820.1971.tb04407.x.