类风湿关节炎患者的QT离散度与心脏受累情况

QT dispersion and cardiac involvement in patients with rheumatoid arthritis.

作者信息

Cindas A, Gökçe-Kutsal Y, Tokgözoglu L, Karanfil A

机构信息

Süleyman Demirel University School of Medicine, Department of Physical Medicine and Rehabilitation, Isparta, Turkey.

出版信息

Scand J Rheumatol. 2002;31(1):22-6. doi: 10.1080/030097402317255327.

DOI:10.1080/030097402317255327

PMID:11922196

Abstract

OBJECTIVE

To investigate the dispersion of repolarization variables in patients with rheumatoid arthritis (RA).

METHODS

Electrocardiography (ECG) and Doppler echocardiography were performed on 40 patients with RA, which were divided into two groups according to the duration of disease and in 48 healthy controls.

RESULTS

All patients had significantly longer QT dispersion (QTd) and corrected QT dispersion (QTc-d) values (p<0.05). The mean values of diastolic function variables were significantly different in all patients compared to healthy controls (p<0.05). There were no statistically significant differences between patient groups in terms of diastolic function variables except IVRT. However, QTd and QTc-d were significantly longer in patients with disease duration over 5 years (p<0.05).

CONCLUSION

We conclude that repolarization heterogeneity and diastolic dysfunction are commonly seen in RA, and QTd is significantly longer in those patients with a disease duration over 5 years compared to those with new onset RA.

摘要

目的

研究类风湿关节炎（RA）患者复极变量的离散情况。

方法

对40例RA患者进行心电图（ECG）和多普勒超声心动图检查，根据病程将其分为两组，并与48例健康对照者进行比较。

结果

所有患者的QT离散度（QTd）和校正QT离散度（QTc-d）值均显著延长（p<0.05）。与健康对照者相比，所有患者舒张功能变量的平均值均有显著差异（p<0.05）。除等容舒张时间（IVRT）外，患者组间舒张功能变量无统计学显著差异。然而，病程超过5年的患者QTd和QTc-d显著更长（p<0.05）。