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纤维肌痛患者的QT离散度和P波离散度

QT dispersion and P wave dispersion in patients with fibromyalgia.

作者信息

Yolbaş Servet, Yıldırım Ahmet, Düzenci Deccane, Karakaya Bülent, Dağlı Mustafa Necati, Koca Süleyman Serdar

机构信息

Department of Rheumatology, Fırat University School of Medicine, Elazığ, Turkey.

Department of Internal Medicine, Fırat University School of Medicine, Elazığ, Turkey.

出版信息

Eur J Rheumatol. 2016 Dec;3(4):165-168. doi: 10.5152/eurjrheum.2016.042. Epub 2016 Dec 1.

Abstract

OBJECTIVE

Fibromyalgia (FM) is a chronic disease characterized by widespread pain. Somatic complaints associated with the cardiovascular system, such as chest pain and palpitations, are frequently seen in FM patients. P and QT dispersions are simple and inexpensive measurements reflecting the regional heterogeneity of atrial and ventricular repolarization, respectively. QT dispersion can cause serious ventricular arrhythmias. The aim of the present study was to evaluate QT dispersion and P wave dispersion in patients with FM.

MATERIAL AND METHODS

The study involved 48 FM patients who fulfilled the established criteria and 32 healthy controls (HC). A standard 12-lead electrocardiogram was performed on all participants. QT dispersion was defined as the difference between the longest and the shortest QT intervals. Similarly, the differences between the shortest and longest P waves were defined as P wave dispersion.

RESULTS

The QT dispersion and corrected QT dispersion were shorter in the FM group compared with the HC group (p<0.001 for both). In terms of the P wave dispersion value, there was no significant difference between the FM and HC groups (p=0.088).

CONCLUSION

Longer QT and P wave dispersions are not problems in patients with FM. Therefore, it may be concluded that fibromyalgia does not include an increased risk of atrial and/or ventricular arrhythmias.

摘要

目的

纤维肌痛(FM)是一种以广泛疼痛为特征的慢性疾病。FM患者经常出现与心血管系统相关的躯体症状,如胸痛和心悸。P波离散度和QT离散度分别是反映心房和心室复极区域异质性的简单且廉价的测量指标。QT离散度可导致严重的室性心律失常。本研究的目的是评估FM患者的QT离散度和P波离散度。

材料与方法

本研究纳入了48例符合既定标准的FM患者和32例健康对照者(HC)。对所有参与者进行标准12导联心电图检查。QT离散度定义为最长QT间期与最短QT间期之差。同样,最短P波与最长P波之间的差异定义为P波离散度。

结果

与HC组相比,FM组的QT离散度和校正QT离散度较短(两者均p<0.001)。就P波离散度值而言,FM组与HC组之间无显著差异(p = 0.088)。

结论

FM患者不存在QT和P波离散度延长的问题。因此,可以得出结论,纤维肌痛不会增加心房和/或室性心律失常的风险。

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