Guillevin L
Service de médecine interne Hôpital Avicenne Université Paris-Nord 93009 Bobigny.
Rev Prat. 2000 Feb 1;50(3):249-54.
Several classifications of systemic vasculitides have been proposed: the Chapel Hill nomenclature, the classification criteria of the American College of Rheumatology and Lie's classification. All have their advantages and disadvantages. The role of ANCA (antineutrophil cytoplasmic antibodies) in classification of vasculitides is now accepted. The classification systems and the contribution of ANCA have led to better distinguishing vasculitis of medium calibre vessels from that involving small vessels, and in particular to distinguish between periarteritis nodosa and microscopic polyangiitis. Polyarteritis nodosa is characterised by involvement of medium calibre vessels (which can lead to vascular nephropathy or other ischemic organ involvement), whereas microscopic polyangiitis can be responsible, among other signs, for glomerulonephritis and pulmonary capillaritis.
查珀尔希尔命名法、美国风湿病学会的分类标准以及李的分类法。它们都各有优缺点。抗中性粒细胞胞浆抗体(ANCA)在血管炎分类中的作用现已得到认可。这些分类系统以及ANCA的作用使得中口径血管性血管炎与小血管性血管炎的区分更加清晰,特别是有助于结节性多动脉炎和显微镜下多血管炎的鉴别。结节性多动脉炎的特征是中口径血管受累(可导致血管性肾病或其他缺血性器官受累),而显微镜下多血管炎除其他症状外,可导致肾小球肾炎和肺毛细血管炎。