Gori F, Anichini C, Novelli L, Pedemonte E, Tozzini S, Dini S
Dipartimento di Patologia Umana ed Oncologia, Università di Firenze, Azienda Ospedaliera di Pistoia.
Pathologica. 2005 Dec;97(6):369-75.
Since etiology and pathogenesis of most systemic and/or isolated vasculitides are unknown, any attempt to make a rational classification of these entities is far from being perfect. Vasculitis may be a primary disease or it may be associated with connective tissue diseases, infectious diseases, neoplasms, drug assumption, allograft rejection and so on. As secondary vasculitides constitute the majority of cases, diagnosis of primary vasculitis is made by exclusion. At the present time, the 1993 Chapel Hill Consensus Conference on Nomenclature of Primary Vasculitides provides a useful guide to clinician and pathologist for evaluating a patient with an idiopathic form of vasculitis. This classification is based on the predominant size of vessels affected and describes the main clinico-pathologic features of the various clearly defined types of systemic vasculitis. Though it suffers from omissions and contradictions, in routine practice it is of great help to distinguish diseases in this intriguing chapter of pathology.
由于大多数系统性和/或孤立性血管炎的病因和发病机制尚不清楚，因此对这些疾病进行合理分类的任何尝试都远非完美。血管炎可能是原发性疾病，也可能与结缔组织病、传染病、肿瘤、药物摄入、同种异体移植排斥等有关。由于继发性血管炎占大多数病例，原发性血管炎的诊断是通过排除法做出的。目前，1993年关于原发性血管炎命名的查珀尔希尔共识会议为临床医生和病理学家评估患有特发性血管炎形式的患者提供了有用的指导。这种分类基于受影响血管的主要大小，并描述了各种明确界定的系统性血管炎类型的主要临床病理特征。尽管它存在遗漏和矛盾之处，但在日常实践中，它对于区分病理学这一有趣章节中的疾病有很大帮助。
