Badescu R C, Lalonde R
Hôtel-Dieu du Centre Hospitalier Universitaire de Montréal.
Rev Neurol (Paris). 2001 Nov;157(11 Pt 1):1410-5.
Correlations were drawn between subscores of a cerebellar motor dysfunction (CMD) scale and simple reaction time (RT) and movement time (MT) in patients diagnosed with olivopontocerebellar atrophy (OPCA). Poor performance on CMD subscores was correlated with long disease duration and lengthening of visual and auditory RT and MT, with the motor speed subscore showing the highest correlations. OPCA patients with severe cerebellar HMPAO uptake deficiency on single photon emission computed tomography scans had poorer performances on three of the four subscores (static equilibrium, dynamic equilibrium and nystagmus, and motor speed) than patients with mild deficiency. These results are discussed in terms of the role of cerebellar afferent/efferent pathways on different types of motor dysfunction in patients with cerebellar atrophy.
对被诊断为橄榄体脑桥小脑萎缩（OPCA）的患者，绘制了小脑运动功能障碍（CMD）量表各子分数与简单反应时间（RT）和运动时间（MT）之间的相关性。CMD子分数表现不佳与病程延长以及视觉和听觉RT及MT延长相关，其中运动速度子分数的相关性最高。在单光子发射计算机断层扫描中显示严重小脑HMPAO摄取缺乏的OPCA患者，在四个子分数中的三个（静态平衡、动态平衡和眼球震颤以及运动速度）上的表现比轻度缺乏的患者更差。根据小脑传入/传出通路在小脑萎缩患者不同类型运动功能障碍中的作用对这些结果进行了讨论。
