Amato Malena M, Esmaeli Bita, Shore John W
Texas Oculoplastic Consultants, 3705 Medical Parkway, Suite 120, Austin, TX 78705, USA.
Ophthalmology. 2002 Apr;109(4):753-6. doi: 10.1016/s0161-6420(01)01012-0.
To report a rare presentation of metastatic orbital rhabdomyosarcoma and the corresponding findings on magnetic resonance imaging (MRI).
Interventional case report.
A 29-year-old white man was diagnosed with rhabdomyosarcoma of the left sinus and orbit for which he was treated with chemotherapy and radiation. Eighteen months after diagnosis, he returned with subacute right eye pain and dysmotility of his extraocular muscles. MRI revealed solitary enlargement of the right medial rectus muscle, and thyroidopathy was suspected. Over the next 2 months, symptoms progressed, and proptosis developed. MRI showed infiltration of seven extraocular muscles. A biopsy of right orbital tissues and the right medial rectus muscle was performed. Special tissue typing confirmed metastatic alveolar rhabdomyosarcoma. The patient underwent palliative radiation therapy and chemotherapy, but he ultimately died of disseminated disease.
Rhabdomyosarcoma can rarely metastasize to the extraocular muscles. Earlier recognition of orbital metastasis through radiographic and biopsy findings, along with prompt and aggressive treatment, may prevent fulminant spread of rhabdomyosarcoma.
报告转移性眼眶横纹肌肉瘤的罕见表现及磁共振成像（MRI）的相应表现。
介入性病例报告。
一名29岁白人男性被诊断为左鼻窦和眼眶横纹肌肉瘤，接受了化疗和放疗。诊断18个月后，他因右眼亚急性疼痛和眼外肌运动障碍复诊。MRI显示右眼内直肌孤立性肿大，怀疑有甲状腺疾病。在接下来的2个月里，症状进展，出现眼球突出。MRI显示7条眼外肌受侵。对右侧眼眶组织和右眼内直肌进行了活检。特殊组织分型确诊为转移性肺泡横纹肌肉瘤。患者接受了姑息性放疗和化疗，但最终死于播散性疾病。
横纹肌肉瘤很少转移至眼外肌。通过影像学和活检结果早期识别眼眶转移，并及时积极治疗，可能预防横纹肌肉瘤的暴发性扩散。
