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小细胞肺癌双侧转移至眼外肌。

Bilateral metastases to the extraocular muscles from small cell lung carcinoma.

作者信息

Crisostomo Sara, Cardigos Joana, Fernandes Diogo Hipólito, Luís Maria Elisa, Pires Guilherme Neri, Duarte Ana Filipa, Boavida Ana Magriço

机构信息

Ophthalmology Department of the Central Lisbon Hospital Center, Lisboa, Portugal.

出版信息

Arq Bras Oftalmol. 2019 Aug 29;82(5):422-424. doi: 10.5935/0004-2749.20190081.

DOI:10.5935/0004-2749.20190081
PMID:31482960
Abstract

Bilateral orbital metastases restricted to the extraocular muscles (EOMs) are exceedingly rare. We report a case of bilateral extraocular muscle metastases from a small cell lung carcinoma and provide a review of the relevant literature. A 56-year-old smoker presented with proptosis, motility changes, and a relative afferent pupillary defect of the left eye, with a previous history of a small cell lung carcinoma. An orbital computerized tomography scan revealed a mass restricted to the left medial rectus. An incisional biopsy confirmed metastasis. Visual acuity of the left eye decreased rapidly, and right globe proptosis became evident. Orbital magnetic resonance imaging at two months follow-up showed marked left orbital mass enlargement and a new right lateral rectus mass. The patient was maintained on palliative care and died from metastatic disease-related complications.

摘要

双侧眼眶转移瘤局限于眼外肌极为罕见。我们报告一例小细胞肺癌导致的双侧眼外肌转移瘤病例,并对相关文献进行综述。一名56岁吸烟者,有小细胞肺癌病史,出现眼球突出、眼球运动改变及左眼相对传入性瞳孔障碍。眼眶计算机断层扫描显示肿块局限于左内侧直肌。切开活检证实为转移瘤。左眼视力迅速下降,右眼眼球突出明显。随访两个月时的眼眶磁共振成像显示左侧眼眶肿块明显增大,右侧外直肌出现新肿块。患者接受姑息治疗,最终死于转移性疾病相关并发症。

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Bilateral metastases to the extraocular muscles from small cell lung carcinoma.小细胞肺癌双侧转移至眼外肌。
Arq Bras Oftalmol. 2019 Aug 29;82(5):422-424. doi: 10.5935/0004-2749.20190081.
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Metastasis of small cell lung cancer to bilateral extraocular muscles: a case report.小细胞肺癌转移至双侧眼外肌:一例报告。
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引用本文的文献

1
Metastasis of small cell lung cancer to bilateral extraocular muscles: a case report.小细胞肺癌转移至双侧眼外肌:一例报告。
J Med Case Rep. 2024 May 2;18(1):216. doi: 10.1186/s13256-024-04525-z.
2
Poorly differentiated orbital neuroendocrine carcinoma.分化不良的眼眶神经内分泌癌。
BMJ Case Rep. 2023 Aug 30;16(8):e254844. doi: 10.1136/bcr-2023-254844.
3
Orbital Metastases: A Systematic Review of Clinical Characteristics, Management Strategies, and Treatment Outcomes.眼眶转移瘤:临床特征、管理策略及治疗结果的系统评价
Cancers (Basel). 2021 Dec 24;14(1):94. doi: 10.3390/cancers14010094.