Mydlík M, Kohút A, Nicák A, Melnicák P
Curr Probl Clin Biochem. 1975;4:240-2.
Authors studied serotonin (5-hydroxytryptamin) in blood in patients with severe renal failure. Changes of serotonin in platelets and plasma in renal failure possibly play a part in clotting disorders of uremia. The authors found increased levels of serotonin in the patients, who suffered from acute and chronic renal failure. 15 patients were dialysed in regular dialysis treatment. Serotonin increased in blood after each dialysis. Platelets remained unchanged during hemodialysis. The authors discuss these new findings and correlate the above mentioned changes with electrolytes and some other laboratory findings.
作者研究了重症肾衰竭患者血液中的血清素（5-羟色胺）。肾衰竭时血小板和血浆中血清素的变化可能在尿毒症凝血障碍中起作用。作者发现急性和慢性肾衰竭患者血清素水平升高。15名患者接受定期透析治疗。每次透析后血液中血清素增加。血液透析期间血小板保持不变。作者讨论了这些新发现，并将上述变化与电解质及其他一些实验室检查结果相关联。
