Jacobi C A, Bonjer H J, Puttick M I, O'Sullivan R, Lee S W, Schwalbach P, Tomita H, Kim Z G, Hewett P, Wittich P, Fleshman J W, Paraskeva P, Gessman T, Neuhaus S J, Wildbrett P, Reymond M A, Gutt C, Whelan R I
Surgical Department, University of Berlin, Charité, Schumannstar. 20 / 21, D-10098 Berlin, Germany.
Surg Endosc. 2002 Mar;16(3):441-5. doi: 10.1007/s00464-001-8112-z. Epub 2001 Dec 10.
Although instrumental manipulation and mechanical tumor cell spillage seem to play the major role in port-site metastases from laparoscopic cancer surgery, minimally invasive procedures are used more and more in the resection of malignancies. However, port-site metastases also have been reported after resection of colon cancer in International Union Against Cancer (UICC) stage I [2, 14]. Therefore, changes in the peritoneal environment during laparoscopy also might influence intra- and extraperitoneal tumor growth during laparoscopy and pneumoperitoneum. Different results of experimental studies presented at the Third International Conference for Laparoscopic Surgery are analyzed and discussed.
尽管器械操作和肿瘤细胞机械性溢出似乎在腹腔镜癌症手术导致的穿刺孔转移中起主要作用，但微创手术在恶性肿瘤切除中的应用越来越多。然而，国际抗癌联盟（UICC）I期结肠癌切除术后也有穿刺孔转移的报道[2,14]。因此，腹腔镜检查期间腹膜环境的变化也可能影响腹腔镜检查和气腹期间腹腔内和腹腔外肿瘤的生长。本文对第三届国际腹腔镜外科学术会议上公布的不同实验研究结果进行了分析和讨论。
