Shimabukuro R H
Environ Qual Saf. 1975;4:140-8.
Glutathione conjugation of foreign compounds is the first step in the mercapturic acid pathway for the detoxication and elimination of toxic compounds in mammals. Plants have been found to metabolize and detoxify some organic herbicides by glutathione conjugation, but the terminal products seem to be different from that in mammals. The terminal product in plants appears to be insoluble residue and not the mercapturic acid derivative which is normally excreted in mammals. The insoluble residue very likely remains in the plant body during the life of the plant. The differences in metabolism between plants and animals may have been necessitated by the lack of an excretory system in plants.
外来化合物的谷胱甘肽结合反应是哺乳动物中硫醚氨酸途径对有毒化合物进行解毒和清除的第一步。已发现植物可通过谷胱甘肽结合反应来代谢和解毒某些有机除草剂，但其终产物似乎与哺乳动物中的不同。植物中的终产物似乎是不溶性残留物，而非哺乳动物中通常排泄出的硫醚氨酸衍生物。这种不溶性残留物很可能在植物的整个生命周期中都留在植物体内。植物和动物在新陈代谢上的差异可能是由于植物缺乏排泄系统所导致的。
