Anić B, Crkvencić N, Mayer M
Zavod za klinicku imunologiju i reumatologiju, Klinika za unutarnje bolesti Medicinskog fakulteta i KBC-a Zagreb, Kispatićeva 12, 10000 Zagreb.
Lijec Vjesn. 2001 Nov-Dec;123(11-12):308-12.
Hypereosinophilia can present a diagnostic problem if initial diagnostic procedures (medical history, physical examination and basic laboratory exams) fail to reveal the cause. Persistent finding of hypereosinophilia in such patients demands diagnostic intervention in order to rule out neoplastic and lymphoproliferative diseases, chronic inflammatory diseases of respiratory and gastrointestinal system and skin, and other inflammatory and postinflammatory conditions. If these disorders are ruled out, consideration should also be given to the diagnosis of primary hypereosinophilia, including idiopathic hypereosinophilic syndrome. The paper presents a patient with significant elevation of absolute and relative numbers of eosinophils in whom the only physical pathologic finding was eosinophilic ascites. Extensive diagnostic investigation did not prove secondary character of abnormalities, and since all pathologic findings receded during 7-month observation without treatment, the conclusion was that the disorder was benign.
如果初始诊断程序（病史、体格检查和基础实验室检查）未能揭示病因，高嗜酸性粒细胞增多症可能会带来诊断难题。在此类患者中持续发现高嗜酸性粒细胞增多症需要进行诊断性干预，以排除肿瘤性和淋巴增殖性疾病、呼吸和胃肠道系统以及皮肤的慢性炎症性疾病，以及其他炎症性和炎症后状况。如果排除了这些疾病，还应考虑原发性高嗜酸性粒细胞增多症的诊断，包括特发性嗜酸性粒细胞增多综合征。本文介绍了一名患者，其嗜酸性粒细胞的绝对数和相对数显著升高，唯一的物理病理发现是嗜酸性腹水。广泛的诊断性调查并未证实异常具有继发性特征，并且由于在7个月的观察期内所有病理发现未经治疗就消退了，所以结论是该疾病为良性。
