Su J C, Birmingham C L
University of British Columbia, Vancouver, Canada.
Eat Weight Disord. 2002 Mar;7(1):20-2. doi: 10.1007/BF03354425.
The clinical manifestations of zinc deficiency and anorexia nervosa are remarkably similar, and a number of studies have demonstrated that there may be a positive correlation between zinc therapy and the rate of recovery of anorexia nervosa patients. However, because of the different interpretations of the results of these studies, the use of zinc supplementation varies. This article examines the evidence supporting zinc supplementation in the treatment of anorexia nervosa. Randomised, double-blind, controlled clinical trials indicate that zinc therapy enhances the rate of recovery in anorexia nervosa patients by increasing weight gain and improving their levels of anxiety and depression. On the basis of these findings and the low toxicity of zinc, zinc supplementation should be included in the treatment protocol for anorexia nervosa.
锌缺乏症和神经性厌食症的临床表现非常相似，多项研究表明，锌疗法与神经性厌食症患者的康复率之间可能存在正相关。然而，由于对这些研究结果的解读不同，锌补充剂的使用情况也有所不同。本文探讨了支持在神经性厌食症治疗中补充锌的证据。随机、双盲、对照临床试验表明，锌疗法通过增加体重和改善焦虑及抑郁水平，提高了神经性厌食症患者的康复率。基于这些发现以及锌的低毒性，补充锌应纳入神经性厌食症的治疗方案中。
