Bard M, Ruffié P
Institut Gustave-Roussy, Département de Médecine, 39, rue Camille Desmoulins, F94805 Villejuif.
Presse Med. 2002 Mar 9;31(9):406-11.
The incidence of malignant pleural mesothelioma has constantly increased over the past forty years. The recent measures of ban on the use of asbestos and the long latency of this tumor after exposure means that its peak incidence can be foreseen for the years 2010-2020.
Various health professionals are involved in the care of this tumor, which benefits equally from progresses in clinical and fundamental research. Some progress has been made in understanding its oncogenesis as well as its histopathologic analysis.
Malignant pleural mesothelioma symptoms are rapidly invalidating and the patient's prognosis is bad at short-term. However, hope may come from the detection of early stages of the disease and from the individualization of good prognosis factors, permitting the selection of patients for whom some curative therapies are in course of evaluation.
在过去四十年中，恶性胸膜间皮瘤的发病率持续上升。近期禁止使用石棉的措施以及该肿瘤在接触后的长时间潜伏期意味着，预计在2010年至2020年期间其发病率将达到峰值。
各类医疗专业人员参与该肿瘤的治疗，临床和基础研究的进展均使其受益。在了解其肿瘤发生机制以及组织病理学分析方面已取得一些进展。
恶性胸膜间皮瘤的症状会迅速导致身体功能丧失，患者短期预后不佳。然而，希望可能来自于疾病早期阶段的检测以及良好预后因素的个体化，这使得能够选择一些正在接受评估性治愈疗法的患者。
