Capner P, Lendrum R, Jeffries D J, Walker G
Gut. 1975 Nov;16(11):866-70. doi: 10.1136/gut.16.11.866.
Viral studies were performed on sera from 54 patients with recent acute pancreatitis, 10 with recurrent acute pancreatitis, seven with chronic pancreatitis, and 10 with pancreatic carcinoma, and on sera from 81 age- and sex-matched controls. In 29 of the acute pancreatitis patients from whom paired sera were obtained no convincing evidence of recent viral infection was found. A higher incidence of raised antibody titres against Coxsackie B3 and B4 was observed in the group of acute pancreatitis patients compared with their controls. The possible signficance of these observations and their relationship to the aetiology of the pancreatitis and to other immunological findings are discussed.
对54例近期患急性胰腺炎的患者、10例复发性急性胰腺炎患者、7例慢性胰腺炎患者和10例胰腺癌患者的血清进行了病毒学研究，并对81名年龄和性别匹配的对照者的血清进行了研究。在29例获得配对血清的急性胰腺炎患者中，未发现近期病毒感染的确凿证据。与对照组相比，急性胰腺炎患者组中抗柯萨奇B3和B4抗体滴度升高的发生率更高。讨论了这些观察结果的可能意义及其与胰腺炎病因和其他免疫学发现的关系。
