Buhlin K, Gustafsson A, Håkansson J, Klinge B
Karolinska Institutet, Institute of Odontology, Department of Periodontology, Stockholm, Sweden.
J Clin Periodontol. 2002 Mar;29(3):254-9. doi: 10.1034/j.1600-051x.2002.290312.x.
The purpose of the present study was to assess the relation between dental health and cardiovascular disease in an adult Swedish population.
A questionnaire was sent to 4811 randomly selected Swedes. It contained 52 questions about dental care habits, oral health, cardiovascular disease and their socio-economic situation. Odd ratios for all cardiovascular diseases (CVD) and the subgroup myocardial infarction, stroke and high blood pressure were calculated with a logistic regression model adjusted for age, gender, smoking, income, civil status and education. These ratios were calculated for subjects > or =41 years since few people suffer from CVD before this.
The national questionnaire was answered by 2839 (59%) people between 20-84 years of age and, of them, 1577 were 41 years of age or more. We found a significant association between self-reported bleeding gums (odds ratio 1.60, p=0.0017), presence of dentures (odds ratio 1.57, p=0.0076) and known CVD, which has also been reported in international studies. However, no association between loose teeth, deep pockets and known CVD was detected.
The results indicate that oral health and, especially gingival inflammation is associated with CVD.
本研究旨在评估瑞典成年人群中牙齿健康与心血管疾病之间的关系。
向4811名随机抽取的瑞典人发放问卷。问卷包含52个关于牙齿护理习惯、口腔健康、心血管疾病及其社会经济状况的问题。使用经年龄、性别、吸烟、收入、婚姻状况和教育程度调整的逻辑回归模型计算所有心血管疾病（CVD）以及心肌梗死、中风和高血压亚组的比值比。由于在此之前很少有人患心血管疾病，因此对年龄≥41岁的受试者计算这些比值比。
2839名年龄在20 - 84岁之间的人（占59%）回答了全国性问卷，其中1577人年龄在41岁及以上。我们发现自我报告的牙龈出血（比值比1.60，p = 0.0017）、佩戴假牙（比值比1.57，p = 0.0076）与已知的心血管疾病之间存在显著关联，国际研究中也有相关报道。然而，未检测到牙齿松动、牙周袋深度与已知心血管疾病之间的关联。
结果表明口腔健康，尤其是牙龈炎症与心血管疾病有关。
