Kalassian Kenneth G, Dremsizov Tony, Angus Derek C
Department of Critical Care Medicine, School of Medicine and Department of Health Services Administration, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Crit Care. 2002 Feb;6(1):11-4. doi: 10.1186/cc1446. Epub 2002 Jan 17.
High quality research evidence is now available to guide and shape the practice of critical care. As the generation of such evidence increases, the challenge facing critical care medicine will be translation of this evidence into measurable improvement in patient outcome. Significant barriers to this process of translation exist that will require substantial effort and resources to overcome. We briefly review the nature of translational barriers to incorporation of research evidence into clinical practice and the conventional approach to surmounting these barriers, and provide examples of barriers and potential solutions to emerging therapies in critical care.
现在已有高质量的研究证据来指导和规范重症监护实践。随着此类证据的不断增加，重症医学面临的挑战将是如何将这些证据转化为患者预后的可衡量改善。这一转化过程存在重大障碍，需要付出巨大努力和资源才能克服。我们简要回顾了将研究证据纳入临床实践的转化障碍的性质以及克服这些障碍的传统方法，并举例说明了重症监护中新兴疗法的障碍及潜在解决方案。
