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冠状动脉搭桥手术后房颤的预测因素。

Predictors of atrial fibrillation after coronary artery bypass graft surgery.

作者信息

Guo Yan, Hu Shengshou, Wu Qingyu, Xu Jianping, Song Yunhu, Zhu Xiaodong

机构信息

Department of Cardiovascular Surgery, Fu Wai Hospital and Cardiovascular Institute, CAMS & PUMC, Beijing 100037, China.

出版信息

Chin Med J (Engl). 2002 Feb;115(2):232-4.

PMID:11940338
Abstract

OBJECTIVE

To identify the clinical predictors of atrial fibrillation (AF) after coronary artery bypass grafting (CABG).

METHODS

322 consecutive patients who had undergone isolated CABG were reviewed. Preoperative, intraoperative and postoperative data were collected. Patients were grouped according to whether AF appeared postoperatively.

RESULTS

AF occurred in 75 patients (23.3%). Most cases of AF (85.6%) appeared on or before the third postoperative day. The mean age for patients with AF was 62.5 years compared with 56.7 years for patients without AF (P < 0.05). The mean aortic crossclamp time for patients with AF was 67 min compared with 60.3 min for patients without AF (P < 0.05). The mean duration of cardiopulmonary bypass for patients with AF was 109.6 min compared with 97.3 min for patients without AF (P < 0.05). The mean duration of mechanical ventilation for patients with AF was 19.1 h compared with 15.7 h for patients without AF (P < 0.05). Multivariate logistic regression analysis was used to identify the following independent predictors of postoperative AF (P < 0.05): age > or = 65 years (OR 2.7; 95% CI 1.5 to 5.1), lesions in the right coronary artery (OR 2.5; 95% CI 1.4 to 4.5), and early postoperative withdrawal of beta blocker (OR 3.9; 95% CI 2.1 to 7.7).

CONCLUSIONS

AF remains the most common complication after CABG. Age and lesions in the right coronary artery can influence the incidence of AF, and beta blocker and magnesium may be the most economical and effective prevention for AF early after CABG.

摘要

目的

确定冠状动脉旁路移植术(CABG)后房颤(AF)的临床预测因素。

方法

回顾了322例连续接受单纯CABG的患者。收集术前、术中和术后数据。根据术后是否出现房颤对患者进行分组。

结果

75例患者(23.3%)发生房颤。大多数房颤病例(85.6%)出现在术后第三天或之前。房颤患者的平均年龄为62.5岁,无房颤患者为56.7岁(P<0.05)。房颤患者的平均主动脉阻断时间为67分钟,无房颤患者为60.3分钟(P<0.05)。房颤患者的平均体外循环时间为109.6分钟,无房颤患者为97.3分钟(P<0.05)。房颤患者的平均机械通气时间为19.1小时,无房颤患者为15.7小时(P<0.05)。采用多因素逻辑回归分析确定以下术后房颤的独立预测因素(P<0.05):年龄≥65岁(OR 2.7;95%CI 1.5至5.1)、右冠状动脉病变(OR 2.5;95%CI 1.4至4.5)以及术后早期停用β受体阻滞剂(OR 3.9;95%CI 2.1至7.7)。

结论

房颤仍然是CABG后最常见的并发症。年龄和右冠状动脉病变可影响房颤的发生率,β受体阻滞剂和镁可能是CABG术后早期预防房颤最经济有效的方法。

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