Senay L C, Fortney S
J Appl Physiol. 1975 Oct;39(4):643-7. doi: 10.1152/jappl.1975.39.4.643.
Five untrained females having no history of heat exposure worked in a cool (16-20 degrees C db, 28% rh) environment on day 1 and a warm environment on day 2 (45 degrees C db, 28% rh). Exercise level (bicycle ergometer) was 30% of individual Vo2 max values and work time on both days was 45 min. Venous blood samples were obtained at rest, after 40 min of exercise and 25 min after exercise ceased. Analysis of blood samples indicated an 8.3% increase in Hct during exercise on day 1 and a plasma volume reduction of 12.8% though total circulating protein increased 11.5%. Except for K+ all parameters approximated control values within 25 min postexercise. On day 2, exercise in heat caused a 12% increase in Hct and a plasma volume reduction of 17.7%. Mean total protein did not significantly change from resting values. These data indicated that for a given % Vo2 max, untrained females suffer considerably greater reductions in plasma volumes than do exercised males. Similar to males, dilatation of the cutaneous vascular bed in unacclimatized females resulted in loss of protein from the vascular volume.
5名无热暴露史的未受过训练的女性在第1天于凉爽环境(干球温度16 - 20摄氏度,相对湿度28%)中工作,在第2天于温暖环境(干球温度45摄氏度,相对湿度28%)中工作。运动强度(自行车测力计)为个体最大摄氧量(Vo2 max)值的30%,两天的工作时间均为45分钟。在静息状态、运动40分钟后以及运动停止25分钟后采集静脉血样。血样分析表明,第1天运动期间血细胞比容(Hct)增加了8.3%,血浆量减少了12.8%,尽管总循环蛋白增加了11.5%。除钾离子外,所有参数在运动后25分钟内接近对照值。在第2天,在高温环境下运动导致血细胞比容增加了12%,血浆量减少了17.7%。平均总蛋白与静息值相比无显著变化。这些数据表明,对于给定的最大摄氧量百分比,未受过训练的女性血浆量的减少幅度比受过训练的男性大得多。与男性相似,未适应环境的女性皮肤血管床扩张导致血管内蛋白质流失。