Schultz U, Idelberger R, Rossaint R, Buhre W
Klinik für Anästhesiologie, Universitätsklinikum der RWTH, Aachen, Germany.
Acta Anaesthesiol Scand. 2002 Feb;46(2):224-6. doi: 10.1034/j.1399-6576.2002.460220.x.
We describe one of the few pediatric cases of central anticholinergic syndrome (CAS) in an 8-year-old boy undergoing elective surgery. Deep sedation, inadequate response to stimuli and reduced muscular tone of the upper airway resulting in airway obstruction were the clinical manifestations of CAS. The symptoms resolved immediately after administration of physostigmine. This case illustrates the importance of considering central anticholinergic syndrome as a differential diagnosis in children if prolonged sedation after general anesthesia occurs.
我们描述了一名8岁接受择期手术男孩发生的为数不多的小儿中枢抗胆碱能综合征（CAS）病例之一。深度镇静、对刺激反应不足以及上呼吸道肌张力降低导致气道阻塞是CAS的临床表现。给予毒扁豆碱后症状立即缓解。该病例说明了如果全身麻醉后出现长时间镇静，应将中枢抗胆碱能综合征作为儿童鉴别诊断的重要性。
