Sara S J, David-Remacle M, Lefevre D
J Comp Physiol Psychol. 1975 Jul;89(5):489-97. doi: 10.1037/h0077053.
Rats were trained in a one-trial passive avoidance task and then were submitted to electroconvulsive shock (ECS) or to sham ECS. Twenty-four hours later they were tested for retention, with the door opened either immediately or 30 sec after the beginning of the test. Rats initially forced to avoid for 30 sec continued to avoid for the entire test, but the others had the usual low step-through latencies seen with ECS-treated animals. Activity measures for those animals stepping through differentiated groups having received footshock from those not having footshock and ECS. A retest 5--10 min later showed "recovery" in the amnestic animals and continued avoidance behavior for those that avoided on the first test. Results are taken as evidence that ECS effects are not on memory storage but on the capacity of the animal to organize information effectively and quickly in order to produce an adaptive response.
大鼠接受单次被动回避任务训练，然后接受电惊厥休克（ECS）或假ECS处理。24小时后对它们进行记忆保持测试，测试开始后立即或30秒后打开门。最初被迫回避30秒的大鼠在整个测试中持续回避，但其他大鼠具有ECS处理动物常见的低步穿潜伏期。对于那些穿过门的动物，活动测量结果区分了接受过电击的组和未接受电击的组以及接受ECS处理的组。5 - 10分钟后的重新测试显示，遗忘动物出现“恢复”，而在第一次测试中回避的动物继续保持回避行为。结果表明，ECS的作用不是影响记忆存储，而是影响动物有效快速组织信息以产生适应性反应的能力。
