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大鼠的新皮质与进食行为

Neocortex and feeding behavior in the rat.

作者信息

Braun J J

出版信息

J Comp Physiol Psychol. 1975 Aug;89(6):507-22. doi: 10.1037/h0077441.

DOI:10.1037/h0077441
PMID:1194455
Abstract

Consummatory behavior and weight-regulation capacity were measured in 12 normal rats and in 43 rats that survived complete (C), sequential unilateral (U), anterolateral (A), or posterior (P) neocortical ablations. Groups C and A displayed aphagia and adipsia followed by a sequence of recovery stages gualitatively identical to, but shorter than, recovery typically seen following lateral hypothalamic lesions. After recovery, Group C displayed long-term effects of finickiness and pradial drinking. These effects as well as a measure of recovery of body-weight-regulation capacity were significantly intercorrelated with lesion size, and body-weight set point remained significantly lower than normal. Group U was relatively unaffected by the first unilateral ablation and showed, relative the second ablation but displayed the long-term effects. Group P, though significantly affected by the lesion, did not display the pattern or intensity of effects described for the other bilaterally ablated groups.

摘要

在12只正常大鼠以及43只经历了完全性(C)、序贯单侧性(U)、前外侧(A)或后侧(P)新皮层切除且存活下来的大鼠中测量了 consummatory 行为和体重调节能力。C组和A组出现摄食和饮水减少,随后是一系列恢复阶段,这些阶段在质量上与下丘脑外侧损伤后通常所见的恢复相同,但持续时间较短。恢复后,C组表现出挑剔和辐射状饮水的长期影响。这些影响以及体重调节能力的恢复程度与损伤大小显著相关,且体重设定点仍显著低于正常水平。U组相对不受首次单侧切除的影响,相对于第二次切除表现出长期影响。P组虽然受到损伤的显著影响,但未表现出其他双侧切除组所描述的效应模式或强度。

相似文献

1
Neocortex and feeding behavior in the rat.大鼠的新皮质与进食行为
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2
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