Wooley O W, Wooley S C, Woods W A
J Comp Physiol Psychol. 1975 Aug;89(6):619-25. doi: 10.1037/h0077455.
Palatable food stimuli were presented to 11 obese and 11 nonobese male human subjects (in three experiments) 1 hr after ingestion of 900-calorie liquid lunches and (on separate days) indentically tasting 450-calorie liquid lunches of equal volume. Salivary responses to the presentation of the stimuli (i.e., appetite) by the nonobese were inhibited by the high-calorie meal, but those by the obses were less inhibited. Hunger ratings were unaffected by calories in either group. Food stimuli were rated as more appetizing by the nonobese after high-calorie meals, but not so by the obese. Parallels with animal findings suggest that salivary responses reflect lateral hypothalamic activity.
在11名肥胖男性和11名非肥胖男性受试者（进行了三项实验）摄入900卡路里的液体午餐1小时后，给他们呈现美味的食物刺激物，并且（在不同日期）给他们呈现等量体积、口味相同的450卡路里液体午餐。高热量餐会抑制非肥胖者对刺激物呈现的唾液反应（即食欲），但对肥胖者的抑制作用较小。两组的饥饿评分均不受卡路里含量的影响。高热量餐后，非肥胖者认为食物刺激物更具吸引力，但肥胖者并非如此。与动物研究结果相似，这表明唾液反应反映了下丘脑外侧的活动。
