• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过眼底反射测量法对活体单眼底层中黑色素、叶黄素和血红蛋白浓度进行无创测量。

Non-invasive measurement of the concentration of melanin, xanthophyll, and hemoglobin in single fundus layers in vivo by fundus reflectometry.

作者信息

Hammer M, Schweitzer D, Thamm E, Kolb A

机构信息

University of Jena, Department of Ophthalmology, Germany.

出版信息

Int Ophthalmol. 2001;23(4-6):279-89. doi: 10.1023/a:1014477925052.

DOI:10.1023/a:1014477925052
PMID:11944852
Abstract

A new model of the reflection of the human ocular fundus on the basis of the adding-doubling method, an approximate solution of the radiative transport equation, is described. This model enables the calculation of the concentration of xanthophyll in the retina, of melanin in the retinal pigment epithelium and in the choroid, and of hemoglobin in the choroid from fundus reflectance spectra. The concentration values found in 12 healthy subjects are in excellent agreement with literature data. In single cases of pathologic fundus alterations possible benefits to the ophthalmologic diagnostics is demonstrated.

摘要

本文描述了一种基于相加-倍增法(辐射传输方程的近似解)的人眼眼底反射新模型。该模型能够根据眼底反射光谱计算视网膜中叶黄素、视网膜色素上皮和脉络膜中黑色素以及脉络膜中血红蛋白的浓度。在12名健康受试者中得到的浓度值与文献数据高度吻合。在个别病理性眼底病变病例中,证明了该模型对眼科诊断可能具有的益处。

相似文献

1
Non-invasive measurement of the concentration of melanin, xanthophyll, and hemoglobin in single fundus layers in vivo by fundus reflectometry.通过眼底反射测量法对活体单眼底层中黑色素、叶黄素和血红蛋白浓度进行无创测量。
Int Ophthalmol. 2001;23(4-6):279-89. doi: 10.1023/a:1014477925052.
2
Quantitative reflection spectroscopy at the human ocular fundus.人眼眼底的定量反射光谱学。
Phys Med Biol. 2002 Jan 21;47(2):179-91. doi: 10.1088/0031-9155/47/2/301.
3
Near-infrared autofluorescence imaging of the fundus: visualization of ocular melanin.眼底近红外自发荧光成像:眼部黑色素的可视化
Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3556-64. doi: 10.1167/iovs.06-0122.
4
Monte Carlo modelling of the spectral reflectance of the human eye.人眼光谱反射率的蒙特卡罗建模。
Phys Med Biol. 2002 Aug 21;47(16):2863-77. doi: 10.1088/0031-9155/47/16/303.
5
Optical characterization of bovine retinal tissues.牛视网膜组织的光学特性
J Biomed Opt. 2004 May-Jun;9(3):624-31. doi: 10.1117/1.1688813.
6
Optical properties of ocular fundus tissues--an in vitro study using the double-integrating-sphere technique and inverse Monte Carlo simulation.眼底组织的光学特性——一项使用双积分球技术和逆蒙特卡罗模拟的体外研究。
Phys Med Biol. 1995 Jun;40(6):963-78. doi: 10.1088/0031-9155/40/6/001.
7
Monte Carlo model for studying the effects of melanin concentrations on retina light absorption.用于研究黑色素浓度对视网膜光吸收影响的蒙特卡罗模型。
J Opt Soc Am A Opt Image Sci Vis. 2008 Feb;25(2):304-11. doi: 10.1364/josaa.25.000304.
8
Quantitative determination of the melanin contents in ocular tissues from human blue and brown eyes.人蓝色和棕色眼睛眼组织中黑色素含量的定量测定。
J Ocul Pharmacol. 1992 Spring;8(1):35-42. doi: 10.1089/jop.1992.8.35.
9
Intraocular distribution of melanin in human, monkey, rabbit, minipig and dog eyes.人眼、猴眼、兔眼、小型猪眼和犬眼的黑色素眼内分布。
Exp Eye Res. 2012 May;98(1):23-7. doi: 10.1016/j.exer.2012.03.004. Epub 2012 Mar 13.
10
Human macular pigment assessed by imaging fundus reflectometry.
Vision Res. 1989;29(6):663-74. doi: 10.1016/0042-6989(89)90028-x.

本文引用的文献

1
Imaging spectroscopy of the human ocular fundus in vivo.
J Biomed Opt. 1997 Oct;2(4):418-25. doi: 10.1117/12.285093.
2
Spectral reflectance of the human ocular fundus.人眼眼底的光谱反射率。
Appl Opt. 1989 Mar 15;28(6):1061-77. doi: 10.1364/AO.28.001061.
3
Aging of the human lens.人晶状体的老化
Appl Opt. 1987 Apr 15;26(8):1437-40. doi: 10.1364/AO.26.001437.
4
Matrix operator theory of radiative transfer. 1: rayleigh scattering.辐射传输的矩阵算子理论。1:瑞利散射。
Appl Opt. 1973 Feb 1;12(2):314-29. doi: 10.1364/AO.12.000314.
5
Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes.作为叶黄素和玉米黄质来源的水果和蔬菜:人眼中的黄斑色素。
Br J Ophthalmol. 1998 Aug;82(8):907-10. doi: 10.1136/bjo.82.8.907.
6
A comparison of the optical Stiles-Crawford effect and retinal densitometry in a clinical setting.临床环境下光学斯泰尔斯-克劳福德效应与视网膜密度测定法的比较。
Invest Ophthalmol Vis Sci. 1998 Jul;39(8):1519-23.
7
Visual influences on diurnal rhythms in ocular length and choroidal thickness in chick eyes.视觉对雏鸡眼睛眼轴长度和脉络膜厚度昼夜节律的影响。
Exp Eye Res. 1998 Feb;66(2):163-81. doi: 10.1006/exer.1997.0420.
8
Widespread choroidal insufficiency in primary open-angle glaucoma.
J Glaucoma. 1997 Feb;6(1):23-32.
9
The pathways of light measured in fundus reflectometry.在眼底反射测量法中测量的光通路。
Vision Res. 1996 Aug;36(15):2229-47. doi: 10.1016/0042-6989(96)00001-6.
10
Decreased choroidal thickness in eyes with secondary angle closure glaucoma. An aetiological factor for deep retinal changes in glaucoma?
Br J Ophthalmol. 1993 Jul;77(7):430-2. doi: 10.1136/bjo.77.7.430.