Hammer M, Roggan A, Schweitzer D, Müller G
Klinikum, Friedrich-Schiller-Universität Jena, Germany.
Phys Med Biol. 1995 Jun;40(6):963-78. doi: 10.1088/0031-9155/40/6/001.
Various models have been published calculating the light transport at the ocular fundus either for interpretation of in vivo reflectance measurements or for the prediction of photocoagulation effects. All these models took the absorption spectra of the pigments located at the ocular fundus, melanin, haemoglobin, xanthophyll, and the photoreceptor pigments, into account. However, light scattering inside the single fundus layers has not been investigated in detail and was, therefore, neglected in the calculations or only considered by very rough approximations. This paper presents measurements on specimens of retina, retinal pigment epithelium, choroid, and sclera using the double-integrating-sphere technique. Absorption coefficients, scattering coefficients, and anisotropy of scattering were calculated by an inverse Monte Carlo simulation from the measured collimated and diffuse transmittance and diffuse reflectance. Conclusions are drawn for the interpretation of fundus reflectance measurements, which are a useful tool in diagnostics and photocoagulation dosimetry.
已经发表了各种模型，用于计算眼底的光传输，以解释体内反射率测量结果或预测光凝效果。所有这些模型都考虑了位于眼底的色素（黑色素、血红蛋白、叶黄素和光感受器色素）的吸收光谱。然而，单个眼底层内的光散射尚未得到详细研究，因此在计算中被忽略，或者仅通过非常粗略的近似来考虑。本文介绍了使用双积分球技术对视网膜、视网膜色素上皮、脉络膜和巩膜标本进行的测量。通过逆蒙特卡罗模拟，根据测量的准直和漫透射率以及漫反射率计算吸收系数、散射系数和散射各向异性。得出了关于眼底反射率测量解释的结论，眼底反射率测量是诊断和光凝剂量学中的一种有用工具。
