Steffensrud S
Pediatrix Medical Group, Tacoma General Hospital, 315 Martin Luther King Way, Tacoma, WA 98405, USA.
Neonatal Netw. 2000 Feb;19(1):9-16. doi: 10.1891/0730-0832.19.1.9.
Symptomatic calcium disorders--most notably, hypocalcemia--are common problems in preterm and certain term infants. Many factors predispose susceptible neonates to hypo- or hypercalcemia, but in many cases, the root of the problem is altered function of the parathyroid glands. Parathyroid gland dysfunction may affect calcium homeostasis and alter physiologic functioning, resulting in significant clinical symptoms. A review of how the parathyroid glands and parathyroid hormone affect calcium balance and of the problems that result from altered function promotes a better appreciation of the important role played by these sometimes "forgotten" glands in maintaining normal neonatal physiologic functioning.
有症状的钙紊乱——最显著的是低钙血症——是早产儿和某些足月儿常见的问题。许多因素使易感新生儿易发生低钙血症或高钙血症,但在许多情况下,问题的根源是甲状旁腺功能改变。甲状旁腺功能障碍可能影响钙稳态并改变生理功能,导致明显的临床症状。回顾甲状旁腺和甲状旁腺激素如何影响钙平衡以及功能改变所导致的问题,有助于更好地认识这些有时被“遗忘”的腺体在维持新生儿正常生理功能中所起的重要作用。