Takeuchi Yukiko, Yoshida Toshinori, Chiba Yuko, Kuwahara Maki, Maita Keizo, Harada Takanori
Toxicology Division II, Institute of Environmental Toxicology, Mistukaido-shi, Ibaraki, Japan.
Toxicol Pathol. 2002 Mar-Apr;30(2):288-91. doi: 10.1080/019262302753559632.
A multicystic mass of the lung was found in a male 11-week-old Wistar Hannover GALAS rat. The cystic mass was located in the region of the right caudal lobe and had no direct communication with the tracheobranchial tree. Histologically, the pulmonary mass was composed of variably sized cysts containing mucinous material, cellular debris, erythrocytes, and inflammatory cells. In the septal stroma between the cysts, well-developed elastic and muscular arteries were present and in some areas, ectopic pancreatic tissue was observed. In the rest of the lung lobes, there was no evidence of previous pneumonic events or other respiratory diseases. Based on these findings, the present case was diagnosed as a congenital pulmonary sequestration with ectopic pancreatic tissue.
在一只11周龄的雄性Wistar Hannover GALAS大鼠中发现了肺部的多囊性肿块。该囊性肿块位于右尾叶区域，与气管支气管树无直接连通。组织学上，肺部肿块由大小不一的囊肿组成，囊肿内含有黏液物质、细胞碎片、红细胞和炎性细胞。在囊肿之间的间隔基质中，存在发育良好的弹性动脉和肌性动脉，在某些区域还观察到异位胰腺组织。在其余肺叶中，没有先前发生肺炎或其他呼吸道疾病的迹象。基于这些发现，本病例被诊断为伴有异位胰腺组织的先天性肺隔离症。
