与TNA相关的碱基配对系统：含有氨基磷酸酯键的α-苏糖呋喃糖基寡核苷酸。
Base-pairing systems related to TNA: alpha-threofuranosyl oligonucleotides containing phosphoramidate linkages.
作者信息
Wu Xiaolin, Guntha Sreenivasulu, Ferencic Mathias, Krishnamurthy Ramanarayanan, Eschenmoser Albert
机构信息
The Skaggs Institute for Chemical Biology at the Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
出版信息
Org Lett. 2002 Apr 18;4(8):1279-82. doi: 10.1021/ol020015x.
PMID:11950342
Abstract
(3'NH)- and (2'NH)-TNA, two isomeric phosphoramidate analogues of TNA (alpha-threofuranosyl-(3'-->2') oligonucleotides), are shown to be efficient Watson-Crick base-pairing systems and to undergo intersystem cross-pairing with TNA, RNA, and DNA. [reaction: see text]
摘要
（3'NH）-和（2'NH）-TNA是TNA（α-苏式呋喃糖基-（3'→2'）寡核苷酸）的两种异构氨基磷酸酯类似物，它们被证明是有效的沃森-克里克碱基配对系统，并能与TNA、RNA和DNA进行系统间交叉配对。[反应：见正文]
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